Goniothalamin from Bryonopsis laciniosa Linn (Cucurbiataceae).
نویسندگان
چکیده
Bryonopsis laciniosa Linn (Cucurbiataceae) is a rare climbing plant, locally known as Shromony (Kirtikar and Basu, 1984; Rahman, 1996). The plant was collected during September 1998 near the village Kakon hat of Borind tract of Rajshahi district, Bangladesh. The plant was identi"ed by Prof. N. Zaman, Dept. of Botany, University of Rajshahi, Bangladesh and a voucher specimen (Voucher specimen no DACB 9400) has been deposited at the Bangladesh National Herbarium.
منابع مشابه
Anti-hyperglycemic and Anti-hyperlipidemic Effects of Bryonia Laciniosa Seed Extract and its Saponin Fraction in Streptozotocin-induced Diabetes in Rats
Bryonia laciniosa Linn. (Cucurbitaceae) seed is used in traditional medicine for a number of ailments including metabolic disorders. This investigation was carried out to investigate the anti-hyperglycemic and anti-hyperlipidemic potential of the ethanolic extract of seeds of B. laciniosa Linn. and its saponin fraction in streptozotocin-induced diabetic rats. The ethanolic extract (250 and 500 ...
متن کاملInduction of caspase-9, biochemical assessment and morphological changes caused by apoptosis in cancer cells treated with goniothalamin extracted from Goniothalamus macrophyllus.
Goniothalamin, a natural compound extracted from Goniothalamus sp. belonging to the Annonacae family, possesses anticancer properties towards several tumor cell lines. This study focused on apoptosis induction by goniothalamin (GTN) in the Hela cervical cancer cell line. Cell growth inhibition was measured by MTT assay and the IC50 value of goniothalamin was 3.2 ± 0.72 μg/ml. Morphological chan...
متن کاملAlkaloids from the roots and leaves of Stichoneuron halabalensis and their acetylcholinesterase inhibitory activities
A study of the hitherto unreported Stichoneuron halabalensis Inthachub led to the characterization of the known compounds (+)-α-tocopherol and (R)-(+)goniothalamin; four known Stemona alkaloids, bisdehydoxystemoninine A (1), stemoninine (2), sessilistemonamine C (3) and sessilistemonamine A (4); and three new alkaloids, stichoneurine C (5), D (6) and E (7). The structures of these compounds wer...
متن کاملSelective cytotoxicity of goniothalamin against hepatoblastoma HepG2 cells.
Liver cancer has become one of the major types of cancer with high mortality and liver cancer is not responsive to the current cytotoxic agents used in chemotherapy. The purpose of this study was to examine the in vitro cytotoxicity of goniothalamin on human hepatoblastoma HepG2 cells and normal liver Chang cells. The cytotoxicity of goniothalamin against HepG2 and liver Chang cell was tested u...
متن کاملInvolvement of Seladin-1 in goniothalamin-induced apoptosis in urinary bladder cancer cells
BACKGROUND Selective Alzheimer Disease Indicator-1 (or Seladin-1) is a multifunctional protein first discovered by downregulation of its expression in Alzheimer's disease. Interestingly, the expression of this protein is upregulated in several cancers, including primary bladder cancer. However, its role in cancer formation has yet to be discovered. Goniothalamin is a natural product that has be...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Biochemical systematics and ecology
دوره 28 10 شماره
صفحات -
تاریخ انتشار 2000